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WHO smallpox vaccine reserve gains support

By on November 18, 2020

first_img The WHA also took a somewhat wary look at two recommendations on smallpox research made by a WHO advisory committee last fall. The World Health Assembly (WHA) “welcomed progress on WHO’s work to establish a global smallpox vaccine reserve,” the WHO said in a statement during the meeting, which ended last week. The effort involves a vaccine stockpile at WHO headquarters in Geneva, plus additional supplies held in participating countries and pledged to WHO for use in an emergency. The agency said it now has 2.5 million doses in Geneva, and member countries have pledged 31 million doses. That includes 20 million doses from the United States and 5 million from France. April 2005 report by WHO Secretariat on recommendations by the Advisory Committee on Variola Virus Researchhttps://apps.who.int/gb/ebwha/pdf_files/WHA58/A58_10-en.pdf Jun 1, 2005 (CIDRAP News) – The World Health Organization’s (WHO’s) plan to build an international emergency stockpile of smallpox vaccine drew support from member countries at their recent annual meeting in Geneva. See also: In 2002 the WHA authorized continued postponement of destruction of the virus, “on the understanding that steps should be taken to ensure that all approved research would remain outcome-oriented and time-limited and kept under review,” the WHO said. In November, the WHO Advisory Committee on Variola Virus Research recommended inserting a green fluorescent marker protein into variola (smallpox) virus to facilitate screening of possible antiviral drugs, the WHO said. “The virus glows green when exposed to an ineffective drug, thus allowing rapid distinction between ineffective and potentially effective drugs against smallpox,” the statement said. May 20 WHO news releasehttp://www.who.int/mediacentre/news/notes/2005/np_wha02/en/index.html April 2005 report by WHO Secretariat on the global smallpox vaccine reservehttps://apps.who.int/gb/ebwha/pdf_files/WHA58/A58_9-en.pdfcenter_img The American pledge of 20 million doses was announced by Tommy Thompson, then secretary of health and human services, last December. Thompson said the nation had more than 400 million doses at that time. The advisory committee also had recommended that researchers be allowed to splice smallpox virus genes into other, less dangerous orthopox viruses for the purpose of testing possible drugs without using the smallpox virus itself. But WHO Diector-General Lee Jong-wook recommended that the committee reconsider that idea, and the WHA concurred with his recommendation, according to McNab. A report by Science magazine’s Sciencenow service said more than half of almost 20 national delegates who spoke at the WHA session voiced worries about the smallpox research proposals. Some urged the WHO to set a firm deadline for the destruction of all remaining stocks of smallpox virus, and others advocated more input from developing countries on the smallpox research agenda, the report said. At its November meeting, the Advisory Committee on Variola Virus Research concluded that no further research involving live smallpox virus was necessary for the sake of developing rapid diagnostic tests, according to a report by the WHO Secretariat. However, the committee reaffirmed the need for live-virus research to develop better vaccines and antiviral drugs, the report says. Smallpox was declared eradicated in 1980, but supplies of smallpox virus are held in two WHO-approved laboratories, one at the US Centers for Disease Control and Prevention and one at a national lab at Koltsovo in Russia. The WHA recommended in 1996 that the virus stocks be destroyed. But in May 1999 the body authorized keeping the stocks temporarily to allow for medical research, in case the disease resurfaces as a result of bioterrorism. In the WHA discussion of this recommendation, WHO spokeswoman Christine McNab told CIDRAP News by e-mail, “The main concerns were for biosafety and biosecurity. Therefore, any proposals to carry out this kind of research would be very carefully examined with these issues in mind before any research was actually approved.” The WHO statement said further that the advisory committee would examine research proposals one at a time. The WHA didn’t take a formal vote on the research recommendations, according to McNab and media reports. A recent report by the WHO Secretariat says plans call for increasing the Geneva stockpile to at least 5 million doses and boosting the reserves held by participating countries to at least 200 million doses. The vaccine would not be used unless smallpox actually re-emerged.last_img read more

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Teen injured in Ripley County crash

By on September 24, 2020

first_imgMilan, Ind. — A Thursday crash near Milan on State Road 350 injured a Moores Hill teen.The Ripley County Sheriff’s Department says a car driven by Catherine Cigolotti, 16, of Moores Hill, was eastbound near Old Mill, at a high rate of speed when she lost control, drove off the south side of the roadway and struck a tree. The force of the crash ripped the engine from the vehicle and trapped the driver. First responders from the Milan Fire Department extricated the victim and transported her with injuries to her lower extremities.Police say wet conditions and excessive speed are contributing factors to the crash.last_img read more

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NBA free agency rumors: Pelicans may be willing to give Al Horford a ‘lucrative deal’

By on August 16, 2020

first_imgHorford was a vital member of the Celtics’ rotation last season. He averaged 13.6 points and 6.7 rebounds while shooting 36% from 3-point range.“It’s something that I haven’t even stopped to think about,” Horford said about free agency last month (via MassLive.com). “I’ve enjoyed being here in Boston. Just have to wait and see what we’re going to do as a team. And it’s steps that the management is going to do moving forward and continue to get better.”The Celtics entered the season as the favorites to win the East but finished with a 49-33 record and were eliminated by the Bucks in five games in the conference semifinals.The Pelicans, meanwhile, have already undergone a major roster overhaul. They completed one of the biggest trades in NBA history earlier this month when they sent Anthony Davis to the Lakers in exchange for Lonzo Ball, Brandon Ingram, Josh Hart and three first-round picks.New Orleans also selected former Duke star Zion Williamson with the No. 1 pick in the 2019 draft last week. Knicks free agency rumors: New York, Julius Randle ‘have mutual interest’ NBA Draft 2019: Zion Williamson wasn’t selected to be Pelicans’ ‘savior’ Horford declined his $30.1 million player option with the Celtics for 2019-20, according to multiple reports, and he had been discussing inking a new three-year deal with the team. But, the two sides are no longer expected to come to an agreement and Horford is likely to sign elsewhere.Horford has a chance to receive a four-year contract, worth around $112 million, this summer, according to a report from the New York Times. Related News Celtics free agency: Boston exploring ‘different opportunities,’ Danny Ainge says Al Horford appears to be generating plenty of interest.The Pelicans are among the teams who could offer Horford a “lucrative deal” this offseason, according to a report from Bleacher Report, which cites unidentified sources. The Mavericks, Clippers, Lakers and 76ers will reportedly all pursue him this summer, as well. “She put her dreams aside for mine.” 🙏After being selected first in the #NBADraft, @Zionwilliamson was emotional as he shared the sacrifices his mom made for this big moment to happen! pic.twitter.com/SpQgDpMqEL— NBA TV (@NBATV) June 21, 2019″(Williamson) is not somebody who is supposed to be the savior of this franchise,” New Orleans executive vice president of basketball operations David Griffin told reporters after the draft. “That’s not what this is. This is a 19-year-old kid who’s going to spend this year learning how to play winning NBA basketball.”The Pelicans also added Jaxson Hayes, Nickeil Alexander-Walker and Marcos Louzada Silva in the draft.last_img read more

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